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ExPlain, from BIOBASE, promotes biological interpretation of high throughput experiments like:
- microarrays
- proteomic data
- ChIP-chip experiments
Software Access
Please register to receive access instructions. Access is Web-based and password-dependent.
Noteworthy Features
- Systematically create experimentally testable hypotheses for gene transcription regulation and signaling networks.
- Map putative transcription factor (TF) binding sites on promoters in focus.
- Construct promoter modules as combinations of individual binding sites and composite regulatory elements, thus suggesting TFs provide common regulation of differentially expressed genes.
- Identify key molecules upstream of TFs that might be responsible for the coordinated regulation of the suggested TFs.
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