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URL:
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http://basic.northwestern.edu/biotools/OligoCalc.html
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What you can do:
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Calculate DNA and RNA single-stranded and double-stranded properties, including molecular weight, solution concentration, melting temperature, estimated absorbance coefficients, inter-molecular self-complementarity estimation and intra-molecular hairpin loop formation.
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Highlights:
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- OligoCalc provides a convenient web interface for calculating the physical properties of DNA and RNA oligonucleotides including melting temperature, molecular weight, %GC content and absorbance coefficient for a given oligonucleotide sequence.
- OligoCalc has a familiar ‘calculator’ look and feel, making it readily understandable and usable.
- OligoCalc incorporates three common methods for calculating oligonucleotide-melting temperatures, including a nearest-neighbor thermodynamic model for melting temperature.
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Keywords:
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- Algorithms
- Base Composition
- Computational Biology/*methods
- DNA/*chemistry
- Models, Chemical
- Oligonucleotides/*chemistry/*genetics
- RNA/*chemistry
- Temperature
- User-Computer Interface
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Literature and Tutorials:
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PubMed Link: OligoCalc -- An online oligonucleotide properties calculator
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This record last updated: 09-28-2007
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