|
Highlights:
|
- MFEprimer evaluates the specificity of PCR primers based on multiple factors, including sequence similarity, stability at the 3'-end of the primer, melting temperature, GC content and number of binding sites between the primer and DNA templates.
- MFEprimer can help the user to select more suitable primers before running either standard or multiplex PCR reactions.
- The cDNA and genomic DNA databases of 10 widely used species, as well as user custom databases, were used as DNA templates for analyzing primers specificity.
- A Primer3Plus server is maintained with a modified Primer3Manager for one-stop primer design and specificity checking.
|