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URL:
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http://babel.ucmp.umu.se/fish/
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What you can do:
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Identify homologous protein domain sequences.
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Highlights:
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- The FISH server is highly accurate in identifying the family membership of domains in a query protein sequence, even in the case of very low sequence identities to known homologues.
- Matches to a query sequence provide the user not only with an annotation of the identified domains and hence a hint to their function, but also with probable 2D and 3D structures, as well as with pairwise and multiple sequence alignments to homologues with low sequence identity.
- In addition, the FISH server allows users to upload and search their own protein sequence collection or to quarry public protein sequence data bases with individual saHMMs.
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Keywords:
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- protein sequence analysis tool
- protein domain analysis tool
- protein sequence similarity analysis tool
- homologous structural domains
- pairwise protein sequence alignment tool
- remote protein sequence alignment tool
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Literature and Tutorials:
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PubMed Link: FISH — family identification of sequence homologues using structure anchored hidden Markov models
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