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URL:
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http://prodata.swmed.edu/compass
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What you can do:
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Construct local alignments and detect homology based on the comparison of multiple sequence alignments
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Highlights:
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- COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles from given MSAs, constructs local profile-profile alignments and analytically estimates E-values for the detected similarities. Until now, COMPASS was only available for download and local installation. Here, we present a new web server featuring the latest version of COMPASS, which provides (i) increased sensitivity and selectivity of homology detection; (ii) longer, more complete alignments; and (iii) faster computational speed. After submission of the query MSA or single sequence, the server performs searches versus a user-specified database. The server includes detailed and intuitive control of the search parameters. A flexible output format, structured similarly to BLAST and PSI-BLAST, provides an easy way to read and analyze the detected profile similarities. Brief help sections are available for all input parameters and output options, along with detailed documentation.
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Keywords:
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- sequence alignment
- sequence homology
- MSA
- Multiple sequence alignment
- protein structure-functional prediction
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Literature and Tutorials:
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PubMed Link: COMPASS server for remote homology inference.
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This record last updated: 10-27-2007
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