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URL:
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http://cbdm.mdc-berlin.de/tools/biasviz/
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What you can do:
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A tool to graphically study local amino acid composition in protein sequences of a multiple sequence alignment.
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Highlights:
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- About a third of all protein sequences have at least one composition biased region (CBR).
- Such regions might act as linkers between protein domains but often confer specific binding to various molecules; therefore, their characterization in terms of their boundaries and over-represented residues is important.
- Analysis of CBRs in a particular sequence can be time consuming if several types of biases have to be explored and their position visualized.
- Assessment of the significance of the detected CBRs can be approached by comparison to homologous protein sequences.
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Keywords:
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- amino acid bias
- protein sequence alignment
- composition biased region
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Literature and Tutorials:
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PubMed Link: BiasViz: visualization of amino acid biased regions in protein alignments
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