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URL:
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http://degradome.uniovi.es
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What you can do:
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Find information on proteases and proteolysis.
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Highlights:
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- The degradome is defined as the complete set of proteases present in an organism.
- The recent availability of whole genomic sequences from multiple organisms has led us to predict the contents of the degradomes of several mammalian species.
- To ensure the fidelity of these predictions, our methods have included manual curation of individual sequences and, when necessary, direct cloning and sequencing experiments.
- The results of these studies in human, chimpanzee, mouse and rat have been incorporated into the Degradome database.
- The annotations about each individual protease can be retrieved by browsing catalytic classes and families or by searching specific terms.
- This web site also provides detailed information about genetic diseases of proteolysis, a growing field of great importance for multiple users.
- Finally, the user can find additional information about protease structures, protease inhibitors, ancillary domains of proteases and differences between mammalian degradomes.
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Keywords:
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- proteolysis
- protease
- human genome
- chimpanzee genome
- mouse genome
- rat genome
- degradome
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Literature and Tutorials:
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PubMed Link: The Degradome database: mammalian proteases and diseases of proteolysis
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This record last updated: 09-15-2008
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