PSORTb v.2.0 -- expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis.

URL:	http://www.psort.org/psortb/index.html
What you can do:	Predict bacterial protein subcellular localizations.
Highlights:	PSORT-B examines a given protein sequence for amino acid composition, similarity to proteins of known localization, presence of a signal peptide, transmembrane alpha-helices and motifs corresponding to specific localizations. A probabilistic method integrates these analyses, returning a list of five possible localization sites with associated probability scores. The program attains a precision of 96% for Gram-positive and Gram-negative bacteria and predictive coverage comparable to other tools for whole proteome analysis. The proportion of proteins at each localization is remarkably consistent across species, even in species with varying proteome size. This dataset, the largest of its kind, is freely available, along with the PSORT-B source code
Keywords:	protein localizations protein subcellular localizations signal peptide prediction tool protein localization prediction tool protein subcellular localization prediction tool bacterial protein subcellular localizations bacterial protein localizations Gram-negative bacteria Gram-positive bacteria signal peptide transmembrane alpha-helices localization signals localization signal prediction
Literature and Tutorials:	PubMed Link: PSORTb v.2.0 -- expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis PubMed Link: PSORT-B: Improving protein subcellular localization prediction for Gram-negative bacteria

This record last updated: 06-15-2005