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Highlights:
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- Nuc-PLoc can be used to identify nuclear proteins among the following nine subnuclear locations: (1) chromatin, (2) heterochromatin, (3) nuclear envelope, (4) nuclear matrix, (5) nuclear pore complex, (6) nuclear speckle, (7) nucleolus, (8) nucleoplasm and (9) nuclear promyelocytic leukaemia (PML) body.
- Nuc-PLoc is featured by an ensemble classifier formed by fusing the evolution information of a protein and its pseudo-amino acid composition.
- The overall jackknife cross-validation accuracy obtained by Nuc-PLoc is significantly higher than those by the existing methods on the same benchmark data set through the same testing procedure.
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