AACompIdent -- Protein identification tool
Identify a protein from its amino acid composition.
 
AAindex -- Amino Acid index database
Search for information on property and similarity of amino acids expressed as numerical values.
 
BioBayesNet -- a web server for feature extraction and Bayesian network modeling of biological sequence data
Model and classify biological data using Bayesian networks
 
CyBase -- a database of cyclic protein sequences and structures, with applications in protein discovery and engineering
Search for curated sequence and structure information on cyclic proteins.
 
DeNovoID -- a web-based tool for identifying peptides from sequence and mass tags deduced from de novo peptide sequencing by mass spectroscopy
Use degenerate amino acid sequence and mass data derived from mass spectroscopy experiments to search a peptide database.
 
EXPASY Proteome Tools Collection
Use a collection of tools for protein analyses.
 
GLUE-IT -- GLUE-Including Translation
Estimate amino acid diversity in libraries with up to 6 variable codons.
 
H++ -- a server for estimating pKas and adding missing hydrogens to macromolecules
Automatically predict protonation equilibrium pK constants of macromolecules based upon their atomic resolution Protein Data Bank (PDB) structures.
 
LINKER -- A web server to generate peptide sequences with extended conformation
Design linker sequences for constructing functional fusion proteins.
 
MPSQ -- Multi-Protein States Query
A web tool for protein state searching.
 
MinActionPath -- maximum likelihood trajectory for large-scale structural transitions in a coarse-grained locally harmonic energy landscape
Generate the most probable trajectory between two states.
 
PBEQ-Solver -- online visualization of electrostatic potential of biomolecules
Calculates and visualizes the electrostatic potential of your molecule by solving the Poisson-Boltzmann (PB) equation.
 
PCE -- web tools to compute protein continuum electrostatics
Perform protein electrostatic computations.
 
PEDEL-AA -- Programme for Estimating Diversity in Error-prone PCR Libraries
Estimate the number of distinct protein variants encoded by an error-prone PCR library.
 
PFIA -- Peptide Fragment Ion Analyser
A tool for the interpretation of tandem mass spectrometric data and de novo sequencing of peptides.
 
PHEPS -- web-based pH-dependent Protein Electrostatics Server
Conduct pH-dependent fast electrostatic analysis.
 
PINT -- Protein–protein Interactions Thermodynamic Database
Search for comprehensive information on protein-protein interaction thermodynamics.
 
PPD v1.0 — an integrated, web-accessible database of experimentally determined protein pKa values
Search for information on protein ionization constants.
 
PROFEAT -- a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence
Compute commonly-used structural and physicochemical features of proteins and peptides from amino acid sequence.
 
Pepinfo/Pepwindow/Pepstats
Find amino acid composition and Kyte & Doolittle hydropathy plot for an amino acid sequence.
 
ProNIT -- A database for protein–nucleic acid interactions
Search for information on protein-nucleic acid interactions.
 
ProSight PTM -- improved protein identification and characterization for top down mass spectrometry
Identify and characterize proteins using mass spectra data from ‘top-down’ fragmentation of intact protein ions (i.e. without any tryptic digestion).
 
ProTherm -- Thermodynamics Database for Proteins and Mutants
Search for thermodynamics information on wild type and mutant proteins.
 
ProtScale -- amino acid scale computation tool
Find the physico-chemical properties ( molecular wt, polarity, hydrophobicity, etc.) of an amino acid sequence by selecting appropriate tools.
 
Qgrid -- Clustering Tool for Detecting Charged and Hydrophobic Regions in Proteins
Quickly locate charged and hydrophobic clusters in proteins.
 
SAPS -- Statistical Analysis tool of Protein Sequences
Evaluate protein sequences by statistical criteria.
 
Selecton -- Server for the Identification of Site-Specific Positive Selection & Purifying Selection
Detect positive and purifying selection using a Bayesian inference approach.
 
TECRdb -- Thermodynamics of enzyme-catalyzed reactions
Search for thermodynamic data on enzyme-catalyzed reactions.
 
TRITON -- a graphical tool for ligand-binding protein engineering
Software for protein engineering.
 
The FoldX web server -- an online force field
Conduct rapid evaluation of the effect of mutations on the stability, folding and dynamics of proteins and nucleic acids.
 
The REFOLD database -- a tool for the optimization of protein expression and refolding
Search for published methods employed in the refolding of recombinant proteins.
 
pKD -- re-designing protein pKa values
Predict changes of protein pKa value due to point mutations.
 

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