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URL:
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http://chem250a.chem.temple.edu/cgi-bin/linker/linker.pl
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What you can do:
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Design linker sequences for constructing functional fusion proteins.
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Highlights:
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- The program automatically generates a set of peptide sequences that are known to adopt extended conformations as determined by X-ray crystallography and NMR.
- In addition to the desired linker sequence length, the web interface provides a number of optional input parameters so that the users may enhance sequence selection based on the requirements of specific applications.
- The output of LINKER includes a list of peptide sequences with specified length and sequence characteristics. A graphical subroutine was implemented to highlight the chemical features of every linker sequence by hydrophobicity plots.
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Keywords:
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- fusion proteins
- protein design
- protein engineering
- linker sequences
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Literature and Tutorials:
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PubMed Link: LINKER
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