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URL:
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http://firedb.bioinfo.cnio.es/
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What you can do:
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Search for functional annotation of important sites in proteins with known structures.
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Highlights:
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- The FireDB database is a databank for functional information relating to proteins with known structures.
- It contains the most comprehensive and detailed repository of known functionally important residues, bringing together both ligand binding and catalytic residues in one site.
- The platform integrates biologically relevant data filtered from the close atomic contacts in Protein Data Bank crystal structures and reliably annotated catalytic residues from the Catalytic Site Atlas.
- The interface allows users to make queries by protein, ligand or keyword. Relevant biologically important residues are displayed in a simple and easy to read manner that allows users to assess binding site similarity across homologous proteins.
- Binding site residue variations can also be viewed with molecular visualization tools.
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Keywords:
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- protein active sites
- protein functional sites
- protein functional annotation
- protein ligand binding sites
- protein catalytic residues
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Literature and Tutorials:
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PubMed Link: FireDB -- a database of functionally important residues from proteins of known structure
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