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URL:
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http://www.mapuproteome.com/
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What you can do:
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Search for information on organellar, cellular, tissue and body fluid proteomes generated by mass spectrometry based proteomics technology.
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Highlights:
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- MAPU contains several body fluid proteomes mapped by mass spectrometry (MS)-based proteomics, including plasma, urine, and cerebrospinal fluid.
- Cell lines have been mapped to a depth of several thousand proteins and the red blood cell proteome has also been analyzed in depth.
- The liver proteome is represented with 3200 proteins.
- MAPU contains the peptides identifying each protein, measured masses, scores and intensities.
- More than 4500 mouse and 2500 human proteins have already been identified in at least one proteome.
- By employing high resolution MS and stringent validation criteria, false positive identification rates in MAPU are lower than 1:1000, making them as reference proteomes in biomarker discovery.
- The new release addresses MS-specific problems including ambiguous peptide-to-protein assignments and it provides insight into general functional features on the protein level ranging from gene ontology classification to comprehensive SwissProt annotation.
- The derived proteomic data are used to annotate the genomes using Distributed Annotation Service (DAS) via EnsEMBL services.
- MAPU 2.0 is a model for a database specifically designed for high-accuracy proteomics and a member of the ProteomExchange Consortium.
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Keywords:
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- body fluid proteomes
- organellar proteome
- plasma proteome
- urine proteome
- tear proteome
- red blood cell proteome
- RBC
- cerebrospinal fluid proteome
- CSF
- Mass spectrometry (MS)-based proteomics
- protein localization
- subcellular localization
- biomarker discovery
- high-accuracy proteome
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Literature and Tutorials:
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PubMed Link: MAPU -- Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes
PubMed Link: High-accuracy proteome maps of human body fluids
PubMed Link: MAPU 2.0 -- Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes
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This record last updated: 01-07-2009
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