APD2 -- the Antimicrobial Peptide Database
What you can do:
Search for detailed information on antimicrobial peptides.
Highlights:
- APD hosts 1228 entries with 65 anticancer, 76 antiviral (53 anti-HIV), 327 antifungal and 944 antibacterial peptides.
- This second version of the database (APD2) allows users to search peptide families (e.g. bacteriocins, cyclotides, or defensins), peptide sources (e.g. fish, frogs or chicken), post-translationally modified peptides (e.g. amidation, oxidation, lipidation, glycosylation or d-amino acids), and peptide binding targets (e.g. membranes, proteins, DNA/RNA, LPS or sugars).
- Statistical analyses reveal that the frequently used amino acid residues (>10%) are Ala and Gly in bacterial peptides, Cys and Gly in plant peptides, Ala, Gly and Lys in insect peptides, and Leu, Ala, Gly and Lys in amphibian peptides.
- Using frequently occurring residues, we demonstrate database-aided peptide design in different ways.
Keywords:
- Antimicrobial Peptides
- AMPs
- antibacterial peptides
- anti-fungal peptides
- antiviral peptides
- anti-tumor peptides
- drug engineering
- Antimicrobial Peptide structures
- Antimicrobial drugs
Literature & Tutorials:
PubMed Link: APD
2009 Update: APD2: the updated antimicrobial peptide database and its application in peptide design
2009 Update: APD2: the updated antimicrobial peptide database and its application in peptide design
This record last updated: 01-07-2009