TRANSPATH xae -- An integrated database on signal transduction and a tool for array analysis
What you can do:
Analyze and visualize gene regulatory networks that combines encyclopedic information on signal transduction pathway.
Highlights:
- This is a commercial database that requires license for access.
- The integration with TRANSFACxae, a database about transcription factors and their DNA binding sites, provides the possibility to obtain complete signaling pathways from ligand to target genes and their products, which may themselves be involved in regulatory action.
- As of 2004, the TRANSPATH Professional release 5.3 contains about 19029 molecules, 4989 genes and 23062 reactions collected from 7177 references.
- With the ArrayAnalyzerTM, an integrated tool has been developed for evaluation of microarray data. It uses the TRANSPATH data set to identify key regulators in pathways connected with up- or down-regulated genes of the respective array.
- The key molecules and their surrounding networks can be viewed with the PathwayBuilderTM, a tool that offers four different modes of visualization.
Keywords:
- signal transduction pathways
- gene regulatory networks
- transcriptional regulatory networks
- microarray data analysis tool
- global gene expression
Literature & Tutorials:
PubMed Link: TRANSPATH
PubMed Link of 2006 update: TRANSPATHxae: an information resource for storing and visualizing signaling pathways and their pathological aberrations
PubMed Link of 2006 update: TRANSPATHxae: an information resource for storing and visualizing signaling pathways and their pathological aberrations
This record last updated: 05-10-2006