T1DBase -- a community web-based resource for type 1 diabetes research
URL:
What you can do:
Enables Type 1 diabetes researchers to analyze, store and share the complex data that biomedical researchers generate in the post-genomic era.
Highlights:
- Currently focused on the molecular genetics and biology of T1D susceptibility and pathogenesis, the database includes the following datasets:
- annotated genome sequence for human, rat and mouse;
- information on genetically identified T1D susceptibility regions in human, rat and mouse, and genetic linkage and association studies pertaining to T1D;
- descriptions of NOD mouse congenic strains; the Beta Cell Gene Expression Bank, which reports expression levels of genes in beta cells under various conditions
- annotations of gene function in beta cells; data on gene expression in a variety of tissues and organs;
- biological pathways from KEGG and BioCarta.
- Tools on the site include the GBrowse genome browser, site-wide context dependent search, Connect-the-Dots for connecting gene and other identifiers from multiple data sources, Cytoscape for visualizing and analyzing biological networks, and the GESTALT workbench for genome annotation.
Keywords:
- Type 1 diabetes
- Juvenile Diabetes
- diabetes
- T1D susceptibility
- T1D pathogenesis
- NOD mouse congenic strains
- Beta Cell Gene Expression
- beta cells
Literature & Tutorials:
PubMed Link: T1DBase -- a community web-based resource for type 1 diabetes research
PubMed Link of 2007 update: T1DBase: integration and presentation of complex data for type 1 diabetes research
2011 Update: T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.
PubMed Link of 2007 update: T1DBase: integration and presentation of complex data for type 1 diabetes research
2011 Update: T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.
This record last updated: 03-27-2007