PDSP (Psychoactive Drug Screening Program) Drug Database
What you can do:
Search for Ki values (affinity constants) for a large number of G-protein coupled receptors (GPCR's), transporters, and ion channels.
Highlights:
- The PDSP Ki database is a unique resource in the public domain which provides information on the abilities of drugs to interact with an expanding number of molecular targets.
- The Ki database serves as a data warehouse for published and internally-derived Ki, or affinity, values for a large number of drugs and drug candidates at an expanding number of G-protein coupled receptors, ion channels, transporters and enzymes.
- The flexible user interface provides for customized data mining.
- The database is updated daily and has a feature for user-supplied data.
- If you are looking for what proteins may bind your test ligand and with what affinity or if you're looking for a ligand to use to identify a receptor, then this database is incredibly useful.
Keywords:
- G-protein-coupled receptors
- GPCR
- G-protein-coupled receptors binding
- protein ligand binding
- G-protein-coupled receptor affinity constants
- ion channel binding
- transporter binding
- Psychoactive Drugs
- ki values
Literature & Tutorials:
PubMed Link of a related review: Molecular biology of serotonin receptors structure and function at the molecular level
This record last updated: 10-25-2006