GLIDA -- GPCR-ligand database for chemical genomic drug discovery
What you can do:
Search for information on G-protein coupled receptors (GPCRs) and their known ligands.
Highlights:
- GLIDA is a public GPCR-related Chemical Genomics database that is primarily focused on the integration of information between GPCRs and their ligands.
- It provides interaction data between GPCRs and their ligands, along with chemical information on the ligands, as well as biological information regarding GPCRs.
- These data are connected with each other in a relational database, allowing users in the field of Chemical Genomics research to easily retrieve such information from either biological or chemical starting points.
- GLIDA includes a variety of similarity search functions for the GPCRs and for their ligands. Thus, GLIDA can provide correlation maps linking the searched homologous GPCRs (or ligands) with their ligands (or GPCRs).
- By analyzing the correlation patterns between GPCRs and ligands, we can gain more detailed knowledge about their conserved molecular recognition patterns and improve drug design efforts by focusing on inferred candidates for GPCR-specific drugs.
Keywords:
- G-protein coupled receptors
- GPCRs
- GPCR-ligand
- GPCR ligands
- G-protein-coupled receptors binding
- protein ligand binding
- GPCRs structures
- protein structures
- GPCR-related drug discovery
- cell surface receptors
- membrane proteins
Literature & Tutorials:
This record last updated: 04-04-2008