KOG - Eukaryotic Orthologous Groups of proteins

What you can do:
Search Clusters of Orthologous Groups of protein (COGs) for seven (nearly) complete eukaryotic genomes.
Highlights:
  • The version of the Clusters of Orthologous Groups of protein (COGs) for seven (nearly) complete eukaryotic genomes, S. cerevisiae, S. pombe, E. cuniculi, the green plant Arabidopsis thaliana, the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster, and Homo sapiens, is currently available.
  • The current set consists of 4852 KOGs which include 60,579 proteins.
  • Detailed analysis of the KOGs revealed various trends in the evolution of eukaryotic genomes including widely different, lineage-specific propensities for gene loss.
  • Manual validation and annotation of the KOGs and update to include additional eukaryotic genomes are underway.
Keywords:
  • protein classification
  • protein phylogeny
  • protein phylogenetic analysis
  • eukaryotic orthologous groups
  • protein phylogenetic lineages
  • human proteins
  • fruitfly proteins
  • Drosophila melanogaster proteins
  • Homo sapiens proteins
  • yeast proteins
  • Saccharomyces cerevisiae proteins
  • Arabidopsis thaliana proteins
  • Schizosaccharomyces pombe proteins
  • Encephalitozoon cuniculi proteins
  • Caenorhabditis elegans proteins
  • eukaryotic genome annotation
  • eukaryotic genome evolution
  • eukaryotic gene evolution
Literature & Tutorials:
This record last updated: 04-17-2014
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