KEGG PATHWAY Database
What you can do:
Search a collection of pathway maps on metabolism, signal transduction, gene regulation, and cellular processes.
Highlights:
- In the KEGG database resource, diseases are viewed as perturbed states of the molecular system, and drugs as perturbants to the molecular system.
- Disease information is computerized in two forms: pathway maps and gene/molecule lists.
- The KEGG PATHWAY database contains pathway maps for the molecular systems in both normal and perturbed states.
- In the KEGG DISEASE database, each disease is represented by a list of known disease genes, any known environmental factors at the molecular level, diagnostic markers and therapeutic drugs, which may reflect the underlying molecular system.
- The KEGG DRUG database contains chemical structures and/or chemical components of all drugs in Japan, including crude drugs and TCM (Traditional Chinese Medicine) formulas, and drugs in the USA and Europe.
- This database also captures knowledge about two types of molecular networks: the interaction network with target molecules, metabolizing enzymes, other drugs, etc. and the chemical structure transformation network in the history of drug development.
- The new disease/drug information resource named KEGG MEDICUS can be used as a reference knowledge base for computational analysis of molecular networks, especially, by integrating large-scale experimental datasets.
Keywords:
- pathway map
- metabolic pathway
- biosynthetic pathway
- signal transduction pathway
- protein biosynthesis pathway
- RNA protein biosynthesis pathway
- cellular process pathway
- human disease
- drug development
- Target Based Structure Classification
- Skeleton Based Structure Classification
- hormone signaling pathways
- olfactory transduction
- cell growth
- cell death
- apoptosis
- receptors
- ABC transporter
Literature & Tutorials:
This record last updated: 02-11-2010