KinMutBase -- Disease-causing protein kinase mutations
What you can do:
Search for comprehensive information on Disease-causing protein kinase mutations.
Highlights:
- KinMutBase is a comprehensive knowledge base for human disease-related mutations in protein kinase domains.
- The 2005 version contains 582 different mutations for 1,790 cases in 1,322 families. KinMutBase entries are described on the DNA, mRNA, and protein level. Numbers for affected patients and families are also provided.
- KinMutBase has extensive amount of links and cross-references to literature, other databases, and information sources.
- There are numerous interactive pages about sequences, structures, mutation statistics, and diseases.
Keywords:
- human protein kinases
- protein kinase mutations
- human genetic disease
- human genetic disorders
- serine/threonine kinase
- tyrosine kinase
Literature & Tutorials:
PubMed Link: KinMutBase, a database of human disease-causing protein kinase mutations
PubMed Link of 2005 update: KinMutBase: a registry of disease-causing mutations in protein kinase domains
PubMed Link of 2005 update: KinMutBase: a registry of disease-causing mutations in protein kinase domains
This record last updated: 06-28-2006