DART -- Drug adverse reaction target database

What you can do:
Search for information on documented adverse reaction targets, functions and properties.
Highlights:
  • The Drug Adverse Reaction Database (DART) is intended to provide comprehensive information about adverse effect targets of drugs described in the literature.
  • Moreover, proteins involved in adverse effect targets of chemicals not yet confirmed as ADR targets are also included as potential targets.
  • This database gives physiological function of each target, binding drugs/agonists/antagonists/activators/inhibitors, IC(50) values of the inhibitors, corresponding adverse effects, and type of ADR induced by drug binding to a target.
  • Cross-links to other databases are also introduced to facilitate the access of information about the sequence, 3-dimensional structure, function, and nomenclature of each target along with drug/ligand binding properties, and related literature.
  • Each entry can be retrieved through multiple search methods including target name, target physiological function, adverse effect, ligand name, and biological pathways. A special page is provided for contribution of new or additional information.
Keywords:
  • adverse drug reactions
  • Drug Interactions
  • adverse effect
  • drug safety
  • drug targets
This record last updated: 07-05-2006
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