DART -- Drug adverse reaction target database
What you can do:
Search for information on documented adverse reaction targets, functions and properties.
Highlights:
- The Drug Adverse Reaction Database (DART) is intended to provide comprehensive information about adverse effect targets of drugs described in the literature.
- Moreover, proteins involved in adverse effect targets of chemicals not yet confirmed as ADR targets are also included as potential targets.
- This database gives physiological function of each target, binding drugs/agonists/antagonists/activators/inhibitors, IC(50) values of the inhibitors, corresponding adverse effects, and type of ADR induced by drug binding to a target.
- Cross-links to other databases are also introduced to facilitate the access of information about the sequence, 3-dimensional structure, function, and nomenclature of each target along with drug/ligand binding properties, and related literature.
- Each entry can be retrieved through multiple search methods including target name, target physiological function, adverse effect, ligand name, and biological pathways. A special page is provided for contribution of new or additional information.
Keywords:
- adverse drug reactions
- Drug Interactions
- adverse effect
- drug safety
- drug targets
Literature & Tutorials:
This record last updated: 07-05-2006