D-HaploDB -- a database of definitive haplotypes determined by genotyping complete hydatidiform mole samples.
What you can do:
Search for information on genome-wide definitive haplotypes, determined using a collection of 74 Japanese complete hydatidiform moles (CHMs), each carrying a genome derived from a single sperm.
Highlights:
- This is a web-accessible resource of genome-wide definitive haplotypes determined from a collection of Japanese complete hydatidiform moles (CHMs), each of which carries a genome derived from a single sperm.
- As of early 2007 the database contains genotypes for 281 439 common SNPs from 74 CHMs which were determined by a high-throughput array-based oligonucleotide hybridization technique.
- The database also presents maps of haplotype blocks and linkage disequilibrium bins together with tagSNPs that might prove useful for association studies of disease genes.
- Cryptic relatedness among the samples in this study is unlikely which was demonstrated by the absence of long extended shared haplotypes (ESHs).
Keywords:
- Japanese complete hydatidiform moles
- extended shared haplotypes
- haplotype blocks
- linkage disequilibrium
- Gestational trophoblastic disease
- human SNPs
- tag SNP
- human disease gene association study
- human genetic variations
- human single nucleotide polymorphisms
- human genotyping
- human haplotype
Literature & Tutorials:
This record last updated: 03-23-2007