MAPU -- Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes

What you can do:
Search for information on organellar, cellular, tissue and body fluid proteomes generated by mass spectrometry based proteomics technology.
Highlights:
  • MAPU contains several body fluid proteomes mapped by mass spectrometry (MS)-based proteomics, including plasma, urine, and cerebrospinal fluid.
  • Cell lines have been mapped to a depth of several thousand proteins and the red blood cell proteome has also been analyzed in depth.
  • The liver proteome is represented with 3200 proteins.
  • MAPU contains the peptides identifying each protein, measured masses, scores and intensities.
  • More than 4500 mouse and 2500 human proteins have already been identified in at least one proteome.
  • By employing high resolution MS and stringent validation criteria, false positive identification rates in MAPU are lower than 1:1000, making them as reference proteomes in biomarker discovery.
  • The new release addresses MS-specific problems including ambiguous peptide-to-protein assignments and it provides insight into general functional features on the protein level ranging from gene ontology classification to comprehensive SwissProt annotation.
  • The derived proteomic data are used to annotate the genomes using Distributed Annotation Service (DAS) via EnsEMBL services.
  • MAPU 2.0 is a model for a database specifically designed for high-accuracy proteomics and a member of the ProteomExchange Consortium.
Keywords:
  • body fluid proteomes
  • organellar proteome
  • plasma proteome
  • urine proteome
  • tear proteome
  • red blood cell proteome
  • RBC
  • cerebrospinal fluid proteome
  • CSF
  • Mass spectrometry (MS)-based proteomics
  • protein localization
  • subcellular localization
  • biomarker discovery
  • high-accuracy proteome
This record last updated: 01-07-2009
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