KBERG -- KnowledgeBase for Estrogen Responsive Genes
What you can do:
Search for comprehensive information on Estrogen Responsive Genes.
Highlights:
- Genes in KBERG were derived from Estrogen Responsive Gene Database (ERGDB) and were analyzed from multiple aspects.
- The authors explored the possible transcription regulation mechanism by capturing highly conserved promoter motifs across orthologous genes, using promoter regions that cover the range of [-1200, +500] relative to the transcription start sites.
- identified motifs are linked to transcription factor binding sites based on the TRANSFAC database.
- In addition, KBERG uses two established ontology systems, GO and eVOC, to associate genes with their function.
- KBERG is a user-friendly system that provides links to other relevant resources such as ERGDB, UniGene, Entrez Gene, HomoloGene, GO, eVOC and GenBank, and thus offers a platform for functional exploration and potential annotation of genes responsive to estrogen.
Keywords:
- estrogen
- estrogen responsive elements
- EREs
- estrogen receptors
- estrogen responsive gene annotation
- estrogen responsive gene promoter analysis
- transcription factor binding sites
Literature & Tutorials:
PubMed Link: KBERG -- KnowledgeBase for Estrogen Responsive Genes
This record last updated: 03-27-2007