FunSimMat -- a comprehensive functional similarity database
What you can do:
Database that provides several different semantic similarity measures for GO terms.
Highlights:
- The Functional Similarity Matrix is a comprehensive database providing various precomputed functional similarity values for proteins in UniProtKB and for protein families in Pfam and SMART.
- Data from the Gene Ontology Annotation project has been added, as well as new functional similarity measures.
- The applicability of the database is greatly extended by the implementation of a new Gene Ontology-based method for disease gene prioritization.
- Two new visualization tools allow an interactive analysis of the functional relationships between proteins or protein families. T
- his is enhanced further by the introduction of an automatically derived hierarchy of annotation classes.
- Additional changes include a revised user front-end and a new RESTlike interface for improving the user-friendliness and online accessibility of FunSimMat.
Keywords:
- Gene Expression Profiling
- Protein Interaction Mapping
- gene ontology
- semantic similarity measures
- GO terms
Literature & Tutorials:
This record last updated: 02-01-2010