Quadbase -- a database of quadruplex motifs
What you can do:
Genome-wide database of G4 DNA--occurrence and conservation in human, chimpanzee, mouse and rat promoters and 146 microbes
Highlights:
- We present a compendium of quadruplex motifs, with particular focus on their occurrence and conservation in promoters-QuadBase.
- It is composed of two parts (EuQuad and ProQuad).
- EuQuad gives information on quadruplex motifs present within 10 kb of transcription starts sites in 99 980 human, chimpanzee, rat and mouse genes.
- ProQuad contains quadruplex information of 146 prokaryotes. Apart from gene-specific searches for quadruplex motifs,
- QuadBase has a number of other modules. 'Orthologs Analysis' queries for conserved motifs across species based on a selected reference organism; 'Pattern Search' can be used to fetch specific motifs of interest from a selected organism using user-defined criteria for quadruplex motifs, i.e. stem, loop size, etc. 'Pattern Finder' tool can search for motifs in any given sequence.
Keywords:
- G4
- quadruplex motifs
- Base Sequence
- Conserved Sequence
- G-Quadruplexes
- Bacteria
- Human
- Genomics
- Guanine
- Mice
- Pan troglodytes
- chimpanzee
- Promoter Regions
- Rats
- Transcription Initiation Site
Literature & Tutorials:
This record last updated: 05-02-2008