ProSA-web -- Protein Structure Analysis

What you can do:
Interactive web service for the recognition of errors in three-dimensional structures of proteins.
Highlights:
  • A major problem in structural biology is the recognition of errors in experimental and theoretical models of protein structures. The ProSA program is an established tool which has a large user base and is frequently employed in the refinement and validation of experimental protein structures and in structure prediction and modeling.
  • The new service presented here is a straightforward and easy to use extension of the classic ProSA program which exploits the advantages of interactive web-based applications for the display of scores and energy plots that highlight potential problems spotted in protein structures.
  • In particular, the quality scores of a protein are displayed in the context of all known protein structures and problematic parts of a structure are shown and highlighted in a 3D molecule viewer.
  • The service specifically addresses the needs encountered in the validation of protein structures obtained from X-ray analysis, NMR spectroscopy and theoretical calculations.
Keywords:
  • Molecular Conformation
  • Protein Conformation
  • Protein Denaturation
  • Protein Folding
  • Sequence Analysis
  • error
  • errors
  • protein structure
This record last updated: 06-04-2008

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