FireDock -- fast interaction refinement in molecular docking
What you can do:
Web server for flexible refinement and scoring of protein-protein docking solutions.
Highlights:
- Includes optimization of side-chain conformations and rigid-body orientation and allows a high-throughput refinement.
- The server provides a user-friendly interface and a 3D visualization of the results.
- A docking protocol consisting of a global search by PatchDock and a refinement by FireDock was extensively tested.
- The protocol was successful in refining and scoring docking solution candidates for cases taken from docking benchmarks.
- We provide an option for using this protocol by automatic redirection of PatchDock candidate solutions to the FireDock web server for refinement.
Keywords:
- protein-protein interactions
- docking
- rigid-body protein-protein docking
Literature & Tutorials:
This record last updated: 07-23-2008