PRRDB -- Pattern Recognition Receptor Database
What you can do:
A comprehensive database of pattern-recognition receptors and their ligands.
Highlights:
- Innate immune system employs a set of receptors called pattern recognition receptors (PRRs) that recognize evolutionarily conserved patterns from pathogens called pathogen associated molecular patterns (PAMPs).
- PRRDB provides extensive information about pattern recognition receptors and their ligands.
- The current version of database contains around 500 patterns recognizing receptors from 77 distinct organisms ranging from insects to human.
- This includes 177 Toll-like receptors, 124 are Scavenger receptors and 67 are Nucleotide Binding Site-Leucine repeats rich receptors.
- The database also provides information about 266 ligands that includes carbohydrates, proteins, nucleic acids, glycolipids, glycoproteins, lipopeptides.
- A number of web tools have been integrated in PRRDB in order to provide following services: i) searching on any field; ii) database browsing; and iii) BLAST search against the pattern-recognition receptors.
- PRRDB also provides external links to standard databases like Swiss-Prot and Pubmed.
Keywords:
- Pattern Recognition Receptors
- PRR
- immunology
- conserved patterns
- pathogen associated molecular patterns
- PAMPs
Literature & Tutorials:
This record last updated: 09-09-2008