SysPimp -- Systematic Platform for Identifying Mutated Proteins

What you can do:
Identify human disease-related mutated proteins within mass spectrometry results.
Highlights:
  • SysPIMP comprises of three layers: (i) a standardized data warehouse, (ii) a pipeline layer for maintaining human disease databases and X!Tandem and BLAST and (iii) a web-based interface.
  • From OMIM AV part, PMD and SwissProt databases, 35,497 non-redundant human disease-related mutated sequences were collected with disease information described by OMIM terms.
  • With the interfaces to browse sequences archived in SysPIMP, X!Tandem, an open source database-search engine used to identify proteins within MS data, was integrated into SysPIMP to help support the detection of potential human disease-related mutants in MS results.
  • In addition, together with non-redundant disease-related mutated sequences, original non-mutated sequences are also provided in SysPIMP for comparative research.
Keywords:
  • mass spectrometry
  • protein mutations
  • human disease
  • homo sapien
This record last updated: 03-15-2010
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