G2Cdb -- The Genes to Cognition Database

URL:

http://www.genes2cognition.org/

What you can do:

A neuroscience database aiming to present a global view of the role of synapse proteins in physiology and disease.

Highlights:

G2Cdb warehouses sets of genes and proteins experimentally elucidated by proteomic mass spectroscopy of signalling complexes and proteins biochemically isolated from mammalian synapse preparations, giving an experimentally validated definition of the constituents of the mammalian synapse.
Automated text-mining and expert (human) curation is used to systematically extracted information from published neurobiological studies in the fields of synaptic signalling electrophysiology and behaviour in knockout and other transgenic mice.
We have also surveyed the human genetics literature for associations to disease caused by mutations in synaptic genes.
The synapse proteome datasets that G2Cdb provides offer a basis for future work in synapse biology and provide useful information on brain diseases.
They have been integrated in a such way that investigators can rapidly query whether a gene or protein is found in brain-signalling complex(es), has a phenotype in rodent models or whether mutations are associated with a human disease.

Keywords:

Literature & Tutorials:

PubMed Link: G2Cdb: the Genes to Cognition database

This record last updated: 01-09-2009