CTD -- Comparative Toxigenomics Database
What you can do:
A curated database that promotes understanding about the effects of environmental chemicals on human health.
Highlights:
- Chemical-gene interactions, chemical-disease relationships and gene-disease relationships are manually curated from the literature, which allows data to be integrated to construct chemical-gene-disease networks.
- Curation focuses on environmental chemicals.
- Interactions are manually curated.
- Interactions are constructed using controlled vocabularies and hierarchies.
- Additional gene attributes (such as Gene Ontology, taxonomy and KEGG pathways) are integrated.
- Data can be viewed from the perspective of a chemical, gene or disease.
- Results and batch queries can be downloaded and saved.
- CTD acts as both a knowledgebase (by reporting data) and a discovery tool (by generating novel inferences).
- Over 116,000 interactions between 3900 chemicals and 13,300 genes have been curated from 270 species, and 5900 gene-disease and 2500 chemical-disease direct relationships have been captured.
- By integrating these data, 350,000 gene-disease relationships and 77,000 chemical-disease relationships can be inferred.
Keywords:
- chemical
- network
- environmental chemicals
- toxicogenomics
Literature & Tutorials:
This record last updated: 01-14-2009