DIANA-microT -- miRNA Target Prediction server

What you can do:
Find information about microRNA targets and function.
Highlights:
  • DIANA-microT is a web server that provides information for predicted miRNA:target gene interactions with a user-friendly interface, providing extensive connectivity to online biological resources.
  • Target gene and miRNA functions may be elucidated through automated bibliographic searches and functional information is accessible through Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.
  • It offers links to nomenclature, sequence and protein databases, and users are facilitated by being able to search for targeted genes using different nomenclatures or functional features, such as the genes possible involvement in biological pathways.
  • The target prediction algorithm supports parameters calculated individually for each miRNA:target gene interaction and provides a signal-to-noise ratio and a precision score that helps in the evaluation of the significance of the predicted results.
  • Using a set of miRNA targets recently identified through the pSILAC method, the performance of several computational target prediction programs was assessed.
  • DIANA-microT 3.0 achieved there with 66% the highest ratio of correctly predicted targets over all predicted targets.
Keywords:
  • microRNA
  • miRNA
  • RNA interference
  • miRNA target prediction
  • gene expression
  • miRNA function
This record last updated: 09-24-2009
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