Find information about genes implicated in human lung cancer, not related to tobacco use.
HLungDB is a database with the integration of the lung cancer-related genes, proteins and miRNAs together with the corresponding clinical information.
The main purpose of this platform is to establish a network of lung cancer-related molecules and to facilitate the mechanistic study of lung carcinogenesis.
The entries describing the relationships between molecules and human lung cancer in the current release were extracted manually from literatures. Currently, we have collected 2585 genes and 212 miRNA involved in lung carcinogenesis have been collected through text mining.
The results from analysis of transcription factor-binding motifs, the promoters and the SNP sites for each gene and have been incorporated.
Since epigenetic alterations also play an important role in lung carcinogenesis, genes with epigenetic regulation were also included.