SelTarbase -- Selective Targets Database
What you can do:
Find information about mononucleotide repeat tracts and microsatellite instability in tumors.
Highlights:
- The Selective Targets database is a curated database of a growing number of public MNR mutation data in microsatellite unstable human tumors.
- Regression calculations for various MSI-H tumor entities indicating statistically deviant mutation frequencies predict TGFBR2, BAX, ACVR2A and others that are shown or highly suspected to be involved in MSI tumorigenesis.
- Many useful tools for further analyzing genomic DNA, derived wild-type and mutated cDNAs and peptides are integrated.
- A comprehensive database of all human coding, untranslated, non-coding RNA- and intronic MNRs (MNR_ensembl) is also included.
Keywords:
- MMR deficiency
- Deficient DNA mismatch repair
- hereditary non-polyposis colorectal cancer
- HNPCC/ Lynch syndrome
- Microsatellite instability
- coding mononucleotide repeat tract
Literature & Tutorials:
This record last updated: 03-16-2010