CDDB -- Conformational Dynamics Data Bank
URL:
What you can do:
Find information about the conformational dynamics of large proteins and protein complexes.
Highlights:
- CDDB is a database that aims to provide comprehensive results on the conformational dynamics of high molecular weight proteins and protein assemblies.
- Analysis is performed using a coarse-grained computational approach that is applied to the majority of structures present in the electron microscopy data bank (EMDB).
- Results include equilibrium thermal fluctuations and elastic strain energy distributions that identify rigid versus flexible protein domains generally, as well as those associated with specific functional transitions, and correlations in molecular motions that identify molecular regions that are highly coupled dynamically, with implications for allosteric mechanisms.
- A web-based search interface enables users to easily collect conformational dynamics data in various formats.
- The data bank is maintained and updated automatically to include conformational dynamics results for new structural entries as they become available in the EMDB.
Keywords:
- protein conformational dynamics
- protein structure
- protein complex structure
Literature & Tutorials:
This record last updated: 06-14-2011