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Pathway Analysis Tools 1
This workshop will introduce open access and commercial biological pathway informatics tools. Major emphasis will be given to:
- NIH DAVID: a comprehensive set of functional annotation tools for investigators to understand biological meaning behind large list of genes (The Database for Annotation, Visualization and Integrated Discovery)
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Ingenuity Pathways Analysis (IPA): a Web-based mammalian biology knowledgebase and analysis tool used for drug discovery and genomic data analysis
- Protein Lounge Pathway Builder 2.0: tool for drawing signal transduction pathways
Participants will learn how to:
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Identify biological interactions among genes of interest
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Connect two molecules with the shortest possible path
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Import a list of genes to arrange into a pathway
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Import Affymatrix gene expression results and display as both a heat map and a pathway map
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Find common upstream and downstream regulators of a gene
- Display array results according to subcellular localization
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Create signal transduction pathways for presentation
- Find statistically over-represented transcription factor binding sites in differentially expressed genes
This class is approved for AMA Category 2 CME credit.
If you have questions, contact the HSLS Molecular Biology Information Service:
Class PowerPoint Presentation
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