The InterPro Database

What you can do:
Identify protein family, domains, patterns, motifs, protein families, and functional sites.
Highlights:
  • The InterPro database integrates together predictive models or 'signatures' representing protein domains, families and functional sites from multiple, diverse source databases: Gene3D, PANTHER, Pfam, PIRSF, PRINTS, ProDom, PROSITE, SMART, SUPERFAMILY and TIGRFAMs.
  • Integration is performed manually and approximately half of the total approximately 58,000 signatures available in the source databases belong to an InterPro entry.
  • The remaining un-integrated signatures have begun to be displayed via the InterPro web interface.
  • Other developments include the provision of non-signature data, such as structural data, in new XML files on our FTP site, as well as the inclusion of matchless UniProtKB proteins in the existing match XML files.
  • The web interface has been extended and now links out to the ADAN predicted protein-protein interaction database and the SPICE and Dasty viewers.
  • The latest public release (v18.0) covers 79.8% of UniProtKB (v14.1) and consists of 16 549 entries. InterPro data may be accessed either via the web address above, via web services, by downloading files by anonymous FTP or by using the InterProScan search software.
Keywords:
  • protein domains
  • protein motifs
  • protein structures
  • protein families
  • protein functional sites
  • protein active sites
  • domain compositions
  • domain architectures
This record last updated: 03-06-2009
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