HPRD -- Human Protein Reference Database
URL:
What you can do:
A database of curated proteomic information pertaining to human proteins.
Highlights:
- All the information in HPRD has been manually extracted from the literature by expert biologists who read, interpret and analyze the published data.
- 2009 changes include PhosphoMotif Finder, which allows users to find the presence of over 320 experimentally verified phosphorylation motifs in proteins of interest.
- Another new feature is a protein distributed annotation system--Human Proteinpedia (http://www.humanproteinpedia.org/)--through which laboratories can submit their data, which is mapped onto protein entries in HPRD.
- Over 75 laboratories involved in proteomics research have already participated in this effort by submitting data for over 15,000 human proteins.
- The submitted data includes mass spectrometry and protein microarray-derived data, among other data types.
- HPRD is also linked to a compendium of human signaling pathways developed by NetPath (http://www.netpath.org/) which currently contains annotations for several cancer and immune signaling pathways.
- Since the last update, more than 5500 new protein sequences have been added, making HPRD a comprehensive resource for studying the human proteome.
Keywords:
- human protein portal
- Protein interactions
- Protein-protein interactions
- human protein domain architectures
- human protein domains
- human enzymes
- human protein Motif
- protein modifications
- human post-translational modifications
- human proteome
- human proteome annotations
- human protein annotations
- human protein pathways
- human disease genes
- human disease proteins
- human cancer genes
- human protein annotation
- human gene annotation
Literature & Tutorials:
PubMed Link: Human Protein Reference Database
2006 Update: Human protein reference database--2006 update
2009 Update: Human Protein Reference Database--2009 update
2006 Update: Human protein reference database--2006 update
2009 Update: Human Protein Reference Database--2009 update
This record last updated: 01-16-2009