siRNA Target Designer (Promega)
What you can do:
Analyzes the input sequence and find regions within that sequence which fit the siRNA Target Design Parameters.
Highlights:
- The siRNA Target Designer program designs oligonucleotides for use with Promega's systems which can be used to produce siRNAs, including siSTRIKEx99 U6 Hairpin Cloning System; siLentGenex99 U6 Cassette RNA Interference System; siLentGene-2x99 U6 Hairpin Cloning System; T7 RiboMAXx99 Express RNAi System; and GeneClipx99 U1 Hairpin Cloning Systems.
- Each siRNA target region, its type, length, percent GC, and location relative to the input sequence, is displayed along with the oligonucleotide sequences needed to generate that siRNA in one of Promega's of DNA-directed RNA Interference systems.
- The context of each of the potential siRNAs found within the input sequence is displayed near the bottom of the output. Clicking on a displayed siRNA sequence will launch a new browser window with a BLAST search of that sequence against the entire GenBank database allowing users to evaluate the expected specificity of that sequence.
Keywords:
- RNA interference
- Knock-down studies
- Small Interfering RNAs
- siRNA
- siRNA design tools
- knock down expression
- RNAi
- gene silencing
Literature & Tutorials:
This record last updated: 05-06-2005