ACLAME -- A CLAssification of Mobile genetic Elements
What you can do:
Search and classify prokaryotic mobile genetic elements (MGEs).
Highlights:
- The ACLAME database is dedicated to the collection, analysis and classification of sequenced mobile genetic elements (MGEs, in particular phages and plasmids).
- In addition to providing information on the MGEs content, classifications are available at various levels of organization.
- At the gene/protein level, families group similar sequences that are expected to share the same function.
- Families of four or more proteins are manually assigned with a functional annotation using the GeneOntology and the locally developed ontology MeGO dedicated to MGEs.
- At the genome level, evolutionary cohesive modules group sets of protein families shared among MGEs.
- At the population level, networks display the reticulate evolutionary relationships among MGEs.
- To increase the coverage of the phage sequence space, ACLAME version 0.4 incorporates 760 high-quality predicted prophages selected from the Prophinder database.
- The BLAST interface for querying the database has been extended and numerous tools for in-depth analysis of the results have been added.
Keywords:
- mobile genetic elements
- MGEs
- MGE
- bacteriophage genomes
- phage genomes
- virus genomes
- transposons
- plasmids
- DNA phages
- lateral gene transfer
- horizontal gene transfer
- prokaryotic mobile genetic elements
- prokaryotic MGEs
- mobile genetic elements classification
Literature & Tutorials:
PubMed Link: ACLAME
-- 2010 Update: ACLAME: a CLAssification of Mobile genetic Elements, update 2010
-- 2010 Update: ACLAME: a CLAssification of Mobile genetic Elements, update 2010
This record last updated: 01-12-2010