DBTSS -- a database of transcriptional start sites
URL:
What you can do:
Search for transcriptional starting sites in human and mouse genomes; conduct comparative promoter analysis.
Highlights:
- DataBase of Transcription Start Sites (DBTSS) is a database which contains precise positional information for transcription start sites (TSSs) of eukaryotic mRNAs.
- The latest update includes 330 million new tags generated by massively sequencing the 5'-end of oligo-cap selected cDNAs in humans and mice.
- The tags were collected from normal fetal or adult human tissues, including brain, thymus, liver, kidney and heart, from 6 human cell lines in 21 diverse growth conditions as well as from mouse NIH3T3 cell line: altogether 31 different cell types or culture conditions are represented.
- This allows DBTSS to faithfully represent the dynamically changing landscape of TSSs in different cell types and conditions, during development and in the course of evolution.
- Differential usage of alternative 5'-ends across cell types and conditions can be viewed in a series of new interfaces.
- Promoter sequence information is now displayed in a comparative genomics viewer where evolutionary turnover of the TSSs can be evaluated.
Keywords:
- transcriptional starting site
- TSS
- transcription start sites
- human genome
- mouse genome
- malaria parasite
- promoters
- promoter analysis
- transcription factor binding site
- TF
- DNA-binding site
- SNPs
- dbSNP
- Zebrafish TSS
- schyzon TSS
- red algae TSS
Literature & Tutorials:
PubMed Link: DBTSS
-- 2006 update: DBTSS: DataBase of Human Transcription Start Sites, progress report 2006
-- 2008 Update: DBTSS: database of transcription start sites, progress report 2008
-- 2010 Update: 2008 Update: DBTSS provides a tissue specific dynamic view of Transcription Start Sites
-- 2006 update: DBTSS: DataBase of Human Transcription Start Sites, progress report 2006
-- 2008 Update: DBTSS: database of transcription start sites, progress report 2008
-- 2010 Update: 2008 Update: DBTSS provides a tissue specific dynamic view of Transcription Start Sites
This record last updated: 01-13-2010