ProTherm -- Thermodynamics Database for Proteins and Mutants
What you can do:
Search for thermodynamics information on wild type and mutant proteins.
Highlights:
- ProTherm is a collection of numerical data of thermodynamic parameters such as Gibbs free energy change, enthalpy change, heat capacity change, transition temperature etc.
- It also contains information about secondary structure and accessibility of wild type residues, experimental conditions (pH, temperature, buffer, ion and protein concentration), measurements and methods used for each data, and activity information (Km and Kcat ).
- ProTherm is cross-linked with sequence databases (PIR and SWISS-PROT), structural database (Protein Data Bank), functional database (Protein Mutant Database), and literature database (PubMed).
- The thermodynamic information is integrated with structural and functional information through the relational database, 3DinSight.
Keywords:
- protein thermodynamics
- mutant proteins
- protein structures
- protein secondary structures
- protein stability
Literature & Tutorials:
PubMed Link: ProTherm
PubMed Link of 2006 update: ProTherm and ProNIT: thermodynamic databases for proteins and protein-nucleic acid interactions
PubMed Link of 2006 update: ProTherm and ProNIT: thermodynamic databases for proteins and protein-nucleic acid interactions
This record last updated: 04-21-2014