The Center for Modeling Human Disease Gene Trap resource

What you can do:
Search for insertions in genes (Gene trap mutagenesis) expressed in mouse embryonic stem cells, under specific in vitro conditions, or based upon sequence identity via an online searchable database.
Highlights:
  • The gene trap insertions are screened using multiplexed in vitro differentiation and induction assays, and sequence tags are generated to complement expression profiles.
  • The clones are available as a resource to researchers worldwide to help to functionally annotate the mammalian genome and will serve as a source to test candidate loci identified by phenotype-driven mutagenesis screens.
Keywords:
  • mouse embryos
  • mouse embryonic stem cells
  • stem cells
  • mutagenesis
  • gene trap mutagenesis
  • gene expression
  • ESTs
  • expressed sequence tags
Literature & Tutorials:
This record last updated: 05-02-2005

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