The Center for Modeling Human Disease Gene Trap resource
What you can do:
Search for insertions in genes (Gene trap mutagenesis) expressed in mouse embryonic stem cells, under specific in vitro conditions, or based upon sequence identity via an online searchable database.
Highlights:
- The gene trap insertions are screened using multiplexed in vitro differentiation and induction assays, and sequence tags are generated to complement expression profiles.
- The clones are available as a resource to researchers worldwide to help to functionally annotate the mammalian genome and will serve as a source to test candidate loci identified by phenotype-driven mutagenesis screens.
Keywords:
- mouse embryos
- mouse embryonic stem cells
- stem cells
- mutagenesis
- gene trap mutagenesis
- gene expression
- ESTs
- expressed sequence tags
Literature & Tutorials:
This record last updated: 05-02-2005