Expresso -- automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee

URL:
http://www.tcoffee.org/Projects_home_page/expresso_home_page.html
What you can do:
Perform high-quality multiple protein sequence alignments.
Highlights:
  • Expresso is a multiple sequence alignment server that aligns sequences using structural information.
  • The server runs BLAST to identify close homologues of the sequences within the PDB database.
  • These PDB structures are used as templates to guide the alignment of the original sequences using structure-based sequence alignment methods like SAP or Fugue.
  • Users can either upload private structures or specify which PDB templates should be used to model each sequence.
  • Expresso delivers sequence alignments with accuracy comparable with structure-based alignments.
Keywords:
  • sequence alignment tool
  • protein sequence alignment tool
  • multiple sequence alignment tool
  • structure-based sequence alignment tool
Literature & Tutorials:
PubMed Link: 3DCoffee@igs -- A Web Server for Combining Sequences and Structures into a Multiple Sequence Alignments
PUbMed Link of 2006 update: Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee
This record last updated: 08-03-2006
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