Expresso -- automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee

What you can do:
Perform high-quality multiple protein sequence alignments.
  • Expresso is a multiple sequence alignment server that aligns sequences using structural information.
  • The server runs BLAST to identify close homologues of the sequences within the PDB database.
  • These PDB structures are used as templates to guide the alignment of the original sequences using structure-based sequence alignment methods like SAP or Fugue.
  • Users can either upload private structures or specify which PDB templates should be used to model each sequence.
  • Expresso delivers sequence alignments with accuracy comparable with structure-based alignments.
  • sequence alignment tool
  • protein sequence alignment tool
  • multiple sequence alignment tool
  • structure-based sequence alignment tool
This record last updated: 08-03-2006
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