PathBLAST -- A Tool for Alignment of Protein Interaction Networks
What you can do:
Compare protein interaction networks across species to identify protein pathways and complexes that have been conserved by evolution.
Highlights:
- It searches for high-scoring alignments between pairs of protein interaction paths, for which proteins of the first path are paired with putative orthologs occurring in the same order in the second path.
- When user specifies a short protein interaction path for query against a target proteinx96protein interaction network selected from a network database, PathBLAST returns a ranked list of matching paths from the target network along with a graphical view of these paths and the overlap among them.
- Target proteinx96protein interaction networks are currently available for Helicobacter pylori, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster.
Keywords:
- protein interactions
- protein-protein interactions
- protein pathways
- protein sequence alignments
- Helicobacter pylori protein-protein interactions
- Saccharomyces cerevisiae protein-protein interactions
- Caenorhabditis elegans protein-protein interactions
- Drosophila melanogaster protein-protein interactions
- fruitfly protein-protein interactions
- yeast protein-protein interactions
- human protein-protein interactions
- mouse protein-protein interactions
Literature & Tutorials:
PubMed Link: PathBlast
This record last updated: 05-12-2005