siDirect -- Target-specific siRNA Design Software for Mammalian RNA Interference

URL:
http://design.rnai.jp/
What you can do:
Design small interfering RNA (siRNA) sequences with maximum target-specificity for mammalian RNA interference.
Highlights:
  • Highly effective siRNA sequences are selected using novel guidelines that were established through an extensive study of the relationship between siRNA sequences and RNAi activity.
  • It avoids off-target gene silencing to enumerate potential cross-hybridization candidates that the widely used BLAST search may overlook.
  • The program accepts an arbitrary sequence as input and quickly returns siRNA candidates, providing a wide scope of applications in mammalian RNAi, including systematic functional genomics and therapeutic gene silencing.
Keywords:
  • RNA interferences
  • RNAi
  • siRNA
  • siRNA design tools
  • mammalian RNAi
  • gene silencing
Literature & Tutorials:
PubMed Link: siDirect
This record last updated: 05-06-2005
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