RESCUE-ESE -- Identifies Candidate Exonic Splicing Enhancers in Vertebrate Exons

What you can do:
Predict splicing phenotypes by identifying sequence changes that disrupt or alter predicted ESEs.
Highlights:
  • RESCUE-ESE has been used in conjunction with experimental validation to identify 238 candidate ESE hexamers in human genes. It has recently been implemented in three additional species: mouse, zebrafish and pufferfish.
  • It annotates RESCUE-ESE hexamers in vertebrate exons to help predicting splicing phenotypes by identifying sequence changes that disrupt or alter predicted ESEs.
Keywords:
  • exonic splicing enhancer
  • ESE
  • gene splicing
  • alternative splicing
  • splicing variants
  • splicing phenotypes
  • introns
  • exons
Literature & Tutorials:
PubMed Link: RESCUE-ESE
This record last updated: 05-09-2005

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