POBO -- Transcription Factor Binding Site Verification with Bootstrapping
What you can do:
Verify putative regulatory motifs.
Highlights:
- POBO can be used to detect, compare and verify predetermined transcription factor binding site motifs in the promoters of one or two clusters of co-regulated genes.
- The program calculates the frequencies of the motif in the input promoter sets. A bootstrap analysis detects significantly over- or underrepresented motifs. The output of the program presents bootstrapped results in picture and text formats.
- statistical tests implemented in POBO can be useful in eliminating false positives from the results of pattern discovery programs and increasing the reliability of true positives.
Keywords:
- DNA-binding sites
- transcription factor binding sites
- promoter analysis
- promoter elements
- regulatory elements
- regulatory motifs
- regulatory sequence analysis tool
Literature & Tutorials:
PubMed Link: POBO
This record last updated: 05-09-2005